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First of all, MDAI” and other research chemical substances available on this website are designed for research and for forensic purposes. MDAI is a research chemical that is a drug designed by a scientist with potential psychoactive and physiological effects. MDAI is manufactured using the molecular formula of C10H11NO2 *HCl. The formula weight is the amount of 213.7 grams per mo. Buy MDPT

The chemical is relatively new , so the physiological and toxicological characteristics of MDAI aren’t well understood. Phenethylamine derivates like 5,6-Methylenedioxy-2-aminoindane might have stimulant and entactogen properties. Buy MDPT

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MDAI can be produced from 3-(3,4-methylenedioxyphenyl)propionic acid[1] which is converted to the acid chloride and then heated to produce 5,6-Methylenedioxy-1-indanone. The treatment of the indanone using amyl-nitrite in methanol and HCl gave the hydroxyimino keto. It is reduced to 2-aminoindan by modifying Nichols earlier method, which was derived in a paper that discussed DOM analogs, [2] by employing a catalyst made of Pd/C glacial acetic acids with catalytic H2SO4.

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MDAI has inhibited the reuptake process of serotonin dopamine, and norepinephrine . MDAI has IC50 values of 512nM 5,920 nM and 1,426 nanomoles, respectively. This suggests MDAI’s affinity with the serotonin-transporter (SERT).

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Furthermore, in animals treated with reserpine or MDAI, higher extracellular concentrations in monoamine neurotransmitters arose and, in particular, serotonin. This suggests MDAI is a potent releaser of serotonin and effective in preventing the reuptake process of serotonin. In comparison MDAI is comparable in capacity to release serotonin to MDA however, it is significantly less powerful than MDMA.

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