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buy 5F-APINACA/5f-akb48 Australia


5F-APINACA (5F-AKB-48) is an analogue of APINACA (AKB-48) fluorinated at the terminal carbon of the pentyl facet chain. It belongs to the class of artificial cannabinoid receptor agonists (SCRAs), that have affinity for CB1 and CB2 receptors with activation of the previous accounting for the psychoactive results of those substances.

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— What is 5F-APINACA —

buy 5F-APINACA/5f-akb48 Australia . 5F-APINACA (5F-AKB-48) is an analogue of APINACA (AKB-48) fluorinated at the terminal carbon of the pentyl facet chain. It belongs to the class of artificial cannabinoid receptor agonists (SCRAs), that have affinity for CB1 and CB2 receptors with activation of the previous accounting for the psychoactive results of those substances. 5F-APINACA is a psychoactive substance and has results much like Δ9-THC, which, according with the Convention on Psychotropic Substances of 1971 . buy 5F-APINACA/5f-akb48 Australia

— (CAS) Registry Number of 5F-APINACA —

– 1400742-13-3

— Other Chemical Names of 5F-AKB-48 —

5F-AKB-48, 5F-AKB48, 5F-APINACA, 5F-APINAKA, AKB-48F, 5-fluoro , AKB48, APINACA N-(5-fluoropentyl) analogue .

— Trade Names of 5F-AKB-48 / Street Names 5F-AKB-48 —

Under the guise of natural incense merchandise, 5F-APINACA is gift in ‘Sweet Leaf C-Liquid’, 5F-AKB-48 – C -Liquid, Aladin Black third Edition, Aladin Legend third
Edition, Super snake green, Super snake white, Black via way of means of LIBIDO, Aladdin black third, Cat eye, Annihilation, Psyclone and Exodus Damnation. In Ireland, a number of merchandise (natural mixtures) containing 5F-AKB-48 had been in circulation.1 Other merchandise containing 5F-APINACA are: Annihilation Vol II, Berries, Berry
Bomb, Black Mamba, Blueberry Kush, Blue Cheese, Bubblegum Kush, Bud Factory – Blueberry Boom, Bud Factory . buy 5F-APINACA/5f-akb48 Australia

– Classic Bud, Bud Factory – Pineapple Haze, Clockwork Orange, Cotton Candy, Exodus Damnation, Exodus Nightshade, Fiji Wild, Genesis, Gold Seal, Head Trip, (happy) Joker – blueberry, (happy) Joker ,juicy fruit, K2 – Black Edition, Kronic – Black Label (cumyl ring analogue), Kronic – Pineapple Express (cumyl ring analogue), Layer Cake, Lemon Haze, Pandora’s Box, Pandora’s Box Unleashed, Paradox Fusion, Psyclone (clown design), Psyclone (purple and white), Rapture, Spellbound, Sweet Leaf, Vertex, buy 5F-APINACA/5f-akb48 Australia

Viper, Voodoo, Voodoo Gold, White Widow, Dutchy, Puff Adder, Exodus, Exodus Damnation and Green Crack.2 5F-APINACA has additionally been detected withinside the e-liquids “Buddha Blues” and “Green fried . buy 5F-APINACA/5f-akb48 Australia

— Physical Appearance 5F-AKB-48 —

White powder.

— Chemical Properties 5F-AKB-48 — buy 5F-APINACA/5f-akb48 Australia

Melting point : 54.9C
Boiling point : now no longer reported
Solubility : sparingly soluble in water; propylene glycol: 2 mg/ml; DMF: 30
mg/ml; ethanol: 30 mg/ml; DMSO: 5 mg/ml

— Identification and Analysis of 5F-AKB-48 —

UV-Visible spectrum: λmax at 209 and 302 nm.five IR-spectrum: Forendex,6 MS,7 GC- MS8, HPLC-TOF, FTIR-ATR

— Ease of Convertibility Into Controlled Substances of 5F-APINACA —

Based on its chemical shape it isn’t always probable that 5F-APINACA may be effortlessly converted
into any other managed substance. buy 5F-APINACA/5f-akb48 Australia

— General Pharmacology 5F-APINACA —

** Routes of management and dosage On the non-commercial, however now no longer peer-reviewed German internet site
“NeuePsychoaktiveSubstanzen.de”10 customers are knowledgeable approximately new psychoactive substances (now no longer peer reviewed). The internet site supplied the subsequent information:
-Usual dose for leisure use is 1-2 mg (inhalation/oral)
-The impact of 5F-APINACA builds up especially fast and disappears additionally rapidly. The period is shorter than AKB-48. 5F-APINACA is generally
seemed as very short-appearing cannabinoid, even supposing it could once in a while purpose a very long ‘afterglow’. buy 5F-APINACA/5f-akb48 Australia

** Pharmacokinetics

No pharmacokinetic research had been defined in clinical literature. The internet site
“NeuePsychoaktiveSubstanzen.de” gives the subsequent information:
Inhalation: Effects inside 30-60 mins with a top impact at 10-30 mins; afterglow: 15-90 mins.
-Oral route: Effects inside 45-180 mins with a top impact at 15-60 mins; afterglow: 60-180 mins.
Metabolism . The metabolism of 5F-APINACA is complicated and extensive, related to mono . buy 5F-APINACA/5f-akb48 Australia

— Toxicology of 5F-APINACA —

**Animal studies **

The genotoxic efficiency of corporations of artificial cannabinoids (SCRAs), i.e., aminoalkylindoles (AM-2201 and UR-144) and 1-alkylindazoles (5F-APINACA and AM-2201-IC) become evaluated in unmarried mobileular gel electrophoresis and micronucleus assays, and in Salmonella/microsome assays.22 All capsules besides AM-2201 prompted DNA-migration and all 4 SCRAs inhibited mobileular department and sizeable induction of micronuclei reflecting structural and numerical chromosomal aberrations (Lowest Observed Effect Level for each outcomes: 50 – 75 μM). buy 5F-APINACA/5f-akb48 Australia

Both corporations increased the stages of nucleoplasmatic bridges which can be fashioned from di-centric chromosomes (chromosome with centromeres), however the frequencies of nuclear buds had been now no longer affected.22 The outcomes withinside the Salmonella assays had been poor. These findings display that those SCRAs purpose chromosomal harm with out inducing gene mutations (poor outcomes in Salmonella assays in absence and presence of metabolic activation). buy 5F-APINACA/5f-akb48 Australia

In evaluation to Δ9-THC, excessive doses (three and six mg/kg, i.p.) of AKB-forty eight and 5F-APINACA precipitated spontaneous and handling-precipitated convulsions, hyperreflexia and myoclonias in
mice; especially 5F-APINACA administered at three and six mg/kg precipitated convulsions in 30 and 90 % of handled animals, respectively. buy 5F-APINACA/5f-akb48 Australia

5F-APINACA at 6 mg/kg precipitated seizures with longer period however with comparable latency as the ones produced through AKB-48.20 5F-APINACA at 3 and 6 mg/kg i.p. precipitated hyperreflexia in 30 and 75 % of mice, respectively which lasted shorter as visible following AKB-48 at 6 mg/kg. 5F-APINACA at 3 and 6 mg/kg i.p. precipitated myoclonia in 90 and 100 % of handled animals with longer latency and period than the ones produced through AKB-forty eight.

These neurological modifications had been blocked through the pre-remedy with the selective CB1 receptor antagonist AM251 (6 mg/kg, i.p. injected 20 min earlier than AKB-48 and 5F-APINACA management).20 Systemic management of 5F-APINACA (0.01–6 mg/kg i.p.) dose-dependently decreased the visible item reaction in mice in any respect doses examined and the impact endured as much as five h of remark simplest for the best doses of substance 3 and 6 mg/kg i.p. (avoided through pre- remedy with AM 251 at 6 mg/kg i.p.). buy 5F-APINACA/5f-akb48 Australia

5F-APINACA inhibited the acoustic reaction in a extended way and the impact seemed to be better than that precipitated through AKB-48 on the equal doses wherein the inhibitory impact endured as much as five h (avoided through pre-remedy with AM 251 at 6 mg/kg i.p.).

The pinnae, corneal and vibrissae reflexes had been dose-dependently decreased through 5F-APINACA (3-6 mg/kg i.p.) (avoided through the pre-remedy with AM 251 at 6 mg/kg i.p.).20 5F-APINACA precipitated a marked catalepsy at three and six mg/kg, and the outcomes remained as much as 270 min. The outcomes had been avoided through the pre-remedy with AM 251 which by myself did now no longer set off akinesia and catalepsy. buy 5F-APINACA/5f-akb48 Australia

***Human research ***

Only little is understood approximately the toxicity of 5F-APINACA in human beings due to the fact few toxicity facts are to be had following (over)dosing of 5F-APINACA. In general, acute signs of SCRA-intoxications consist of tachycardia, hypertension, nausea/vomiting, hypokalemia, agitation, hallucinations, somnolence, mydriasis, chest ache, myoclonia, seizures, and acute psychotic reactions.23 Symptoms normally disappear inside some hours.

Most of the signs are much like the ones after the usage of hashish in excessive-dose, besides for agitation and seizures which might be normally now no longer visible after excessive doses of hashish.24 Anxiety, paranoia, dry mouth, headache, hyperthermia had been suggested via way of means of customers of buy 5F-APINACA/5f-akb48 Australia

— Adverse 5F-APINACA Reactions in Humans —

It isn’t always feasible to attract conclusions approximately unfavorable reactions to 5F-APINACA in human beings due to the fact few toxicity facts are to be had following overdosing. In general, acute signs of SCRA intoxications consist of tachycardia, hypertension, nausea/vomiting, hypokalemia, agitation, hallucinations, somnolence, mydriasis, chest ache, myoclonic seizures, and acute psychotic reactions. buy 5F-APINACA/5f-akb48 Australia

Symptoms normally disappear inside some hours. Most of the signs are much like the ones after the usage of hashish in excessive-dose, besides for agitation and seizures which might be normally now no longer visible after excessive doses of hashish.24 Anxiety, paranoia, dry mouth, headache, and hyperthermia had been suggested on consumer blogs and boards via way of means of customers of 5F-APINACA. buy 5F-APINACA/5f-akb48 Australia

— Dependence Potential of 5F-APINACA —

*** Animal Studies

No research the usage of self-administration, conditioned area desire or discriminative conduct had been defined.

*** Human Studies

Herbal combinations containing 5F-APINACA are unexpectedly addictive merchandise as individuals defined speedy followed structured use styles and routines. buy 5F-APINACA/5f-akb48 Australia

Following the use among one and 4 grams according to day in first-time experimentation, the quantity of use elevated speedy. Compulsive re-dosing passed off notwithstanding reputation of lack of control, focus of tolerance and fears round unfavourable effects. The improvement of mind and cravings approximately smoking first element withinside the morning evolved unexpectedly following preliminary styles of use of 5F-APINACA.

*** Withdrawal of 5F-APINACA / 5f-akb48

Acute bodily withdrawal signs whilst trying to limition use, covered chest pains, chest pressure, tachycardia and palpitations, decrease extremity ache and
spasms, nausea, sweating, diarrhea, and vomiting, which have been effortlessly resolved via way of means of resuming smoking of 5F-APINACA. Psychological withdrawal signs covered ongoing insomnia (for over three weeks), inner restlessness, urge to re-dose, anxiety, agitation and paranoia. buy 5F-APINACA/5f-akb48 Australia

— Current International Controls and Their Impact —

5F-APINACA isn’t always scheduled below the 1971 United Nations Convention on Psychotropic .Substances or the 1961 Single Convention on Narcotic Drugs

— Where to buy 5F-AKB-48 —

You should buy 98% herbal 5F-AKB-48 crystal with Auschem21 . We provide incredible research chemicals / Cannabinoids and Synthetic pills with incredible shipping and Discreet shipping . We supply interior Australia to Scotland , Indonesia , Thailand , Philippines , Singapore , New Zealand , Japan , Taiwan , Malaysia and distinctive countries thru our chain of expert middlemen . buy 5F-APINACA/5f-akb48 Australia

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