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4-Fluoromethamphetamine (4-FMA) is a stimulant drug related to methamphetamine and 4-fluoroamphetamine. It has been reported to be sold as a designer drug, but little is known about its pharmacology or toxicology. Anecdotal user reports however mention a high risk of physical dependence and serious withdrawal symptoms, such as fever and a tendency for dissociation, which last about a week.


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buy 4-fea online . 4-Fluoromethamphetamine (also known as 4-FMA) is a lesser-known novel stimulant-entactogen substance of the amphetamine class. 4-FMA is chemically related to 4-FA and methamphetamine. Little is known about its pharmacology, but it likely produces its effects by increasing levels of dopamine, norepinephrine, and serotonin in the brain.

4-FMA was first detected being sold in Japan as a legal high in 2006.[1] It has been sold online as a research chemical alongside 2-fluoroamphetamine (2-FA), 3-fluoroamphetamine (3-FA) and 4-fluoroamphetamine (4-FA).[2][3] When 4-FA was made illegal in the Netherlands in 2017, 4-FMA grew in popularity as a legal substitute, due to their similar names and effects.[4] In 2018, the number of analyzed 4-FA samples increasingly contained 4-FMA (and/or other fluorinated amphetamines) and the availability of actual 4-FA decreased sharply.[5]

User reports describe the effects of 4-FMA as having characteristics of both traditional stimulants like amphetamine and entactogens like MDMA. Its effects have been described as subjectively lying between 4-FA and 2-FMA. It has been reported to be more likely to produce side effects like headaches and cardiovascular effects than similar substances.

Very little is known about the pharmacological properties, metabolism, and toxicity of 4-FMA. 4-FMA use may produce dependence and abuse as well as damage to the brain and other organs. It is highly advised to use harm reduction practices if using this substance.

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4-Fluoromethamphetamine (4-FMA) is a synthetic molecule of the substituted amphetamine family. Molecules of this class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. The term “amphetamine” is the contracted form of alpha-methylphenethylamine. 4-fluoromethamphetamine contains a fluorine atom at R4 of its phenyl ring and is therefore a fluorinated analogue of methamphetamine.

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Similar to its structural analog 4-FA, 4-Fluoromethamphetamine is thought to act as a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine, producing stimulating amphetamine-like effects at lower doses and more euphoric, entactogen effects similar to MDA at dosages above 125mg. [avoid opinion] Researchers have found some evidence that indicates some similarities between the “Serotonin Release” of 4-FMA and other popular empathogens such as: MDA, 4-Methylmethcathinone, and 4-fluoroamphetamine. . buy 4-fea online

The mechanism of action of 4-FMA effectively boosts the levels of the norepinephrine, dopamine, and serotonin neurotransmitters in higher doses in the brain by binding to and partially blocking the transporter proteins that normally clear these monoamines from the synaptic cleft. This allows dopamine, norepinephrine, and serotonin to accumulate within various regions of the brain, including its reward pathways, resulting in stimulating, euphoric and entactogenic effects.

4-FMA is a CYP450 inhibitor. It reduces the metabolism of methamphetamine, which has the effect of increasing its potency, duration and systemic toxicity while also reducing its cellular toxicity.

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In low doses, 4-FMA has been reported to be a lackluster nootropic for general productivity.[citation needed] Such usage would be strongly discouraged however, due to the increased risks for neurotoxicity and other dangerous side-effects. The reasoning for this warning is based on the studies showing that 4-FMA is similar to MDA, and belongs to the entactogen class.

Using any entactogen frequently is considered dangerous, and it is seen as unwise to take “microdoses” below the minimum dose required to experience a “roll” with members of the entactogen class. At higher dosages, it is known to become dysfunctional and recreational due to the scattering quality of its euphoria and stimulation . buy 4-fea online

Similar to MDA, MDMA, 4-FA,

substances that produce distinct pleasurable tactile “roll”-like sensations, which is typically linked to serotonin-releasing properties, 4-FMA has been reported to be able to produce similar entactogenic effects in addition to traditional stimulant ones. Some reports suggest it tends to come with more side effects and bodily strain than other fluorinated amphetamines, explaining its lack of popularity and availability. buy 4-fea online

Disclaimer: The effects listed below of 4-fea

online is the Subjective Effect Index (SEI), a research literature based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be regarded with a healthy degree of skepticism. It is worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become much more likely with higher doses and may include addiction, serious injury, or death. buy 4-fea online


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Based on 16 reviews

4.7 overall

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